Date: Thursday September 15, 2016 at noon
Location: 223 Herman Brown Hall, Rice University
Date: Thursday September 15, 2016 at noon
Location: 223 Herman Brown Hall, Rice University
Date: Thursday October 8, 2015 at noon
Location: 223 Herman Brown Hall, Rice University
Proton range verification is a very important issue in proton radiation therapy since critical organs can be located just beyond the proton range. 18O, 63Cu and 68Zn were studies as proton range verification materials since they are strongly activated by low energy protons and decay with positron emissions. We used some of these elements to develop patient implantable hydrogel fiducial markers which are PET visible. They can be used as universal fiducial markers due to their CT/PET/MRI/US visibility and also as the proton therapy/range verification markers.
We developed hybrid bi-metallic nanoparticles – Zn@Au (Zn core and Au shell). When irradiated with protons using a medical cyclotron, the Zn cores are activated to decay with positron emission with relatively long half-lives. Therefore, PET imaging shows the in-vivo distribution of those injected nanoparticles. The developed Zn@Au nanoparticles have near identical radiosensitization as gold nanoparticles (GNPs) of the same size. Therefore, the Zn@Au nanoparticles may enable PET image guided GNP mediated radiation therapy as well as molecular imaging.
https://research.okstate.edu/venture-i
http://physics.okstate.edu/www/medical-physics.html
Date: Thursday September 17, 2015 at noon
Location: 223 Herman Brown Hall, Rice University